Syrian state TV has reported a powerful explosion has hit the nation's capital, causing an unknown number of casualties.
State TV said Saturday evening that the blast shook the Damascus neighborhood of Ruken al-Deen late Saturday.
Residents confirmed to news wires that they heard a large explosion.
At least three people are said to have been killed in the blast.
According to RT, initial reports said the blast was caused by a car bomb and that experts are dismantling other explosives in the area.
No further details were immediately available.
Israel reportedly attacked three sites in Syria two weeks ago, in an effort to prevent chemical weapons from reaching Hizbullah.