It's simple. In the new cancer test kit developed by Zetiq Technologies, if the cells in a tissue test stain green, they are normal. If they stain red they are cancerous. Dr. Adi Elkeles, CEO of Zetiq, called the test "a very simple discrimination that can be analyzed even by a layman."

"There is a huge need for simple tools that can screen and diagnose all types of cancer," he added. "Early detection can make all the difference between life and death. Hundreds of millions of people will need this technology. It offers a major breakthrough in the field of cancer diagnostics."

The new technology – dubbed CellDetect – uses a metabolic signature, developed using clinical tissue samples, to distinguish between normal and malignant cells.

This is crucial because a large cell population will often contain only a very small number of malignant cells. Using traditional diagnostic techniques these cells are often undetected because they are so scarce in nu

The test that could save millions of lives was developed by a company that employs only five people.

mber, or because the distinction between the cells and the background is so minor.

Just five people

Using CellDetect, the difference between malignant and normal cells is clear. "It's like moving from a black and white TV to color," said Ami Eyal, the CEO of parent company Bio-Light Life Science Investments. "We bring a visualization tool into the field that will revolutionize the way people do diagnosis based on looking at cells. You can't miss the cells, they are red."

Another advantage over traditional tests and biopsies, said Elkeles, is the fact that the test can be used to detect a wide range of different cancers, something he claims no other diagnostic tool can do. In addition, it can be used for drug development. "This has great clinical and business value," he told ISRAEL21c.

From the CellDetect product brochure.

Zetiq Technologies

The test that could save millions of lives was developed by a company that employs only five people, and outsources the rest of its work in Israel and abroad. "We don't need a big infrastructure," explained Elkeles.

Tailoring tests

The company's first application for this platform technology is a diagnostic tool for cervical cancer. Abo

"Our technology can stain most, if not all, cancer cells."

ut 10,000 women are diagnosed with this disease in the US every year, and about 3,700 women die of it, according to statistics from the National Cervical Cancer Coalition.

Aside from this, the company is working on diagnostic tools for other types of cancer. "Our technology can stain most, if not all, cancer cells," says Elkeles. "We can tailor the right test for different types of cancer."

CellDetect has proven successful in pre-clinical trials. Further clinical trials will begin later this year, though Elkeles declined to give details.

Good for drug scientists too

The company also plans to develop the technology for scientists working in research and drug discovery. For drug discovery purposes, the metabolic signature can be used to detect whether a chemical or biological compound has changed the phenotype of cell lines from cancerous to normal, or vice versa.

Zetiq, which is headquartered in Ramat Gan, was founded six years ago and is based on research by Israeli scientists. The company is now a fully owned subsidiary of Bio-light, a management and holding company specializing in biomedical technologies.

Bio-Light, a Tel Aviv Stock Exchange company, has three other biotech companies in its portfolio - OBEcure, allergica and IOPtima