Residents of rebel-held parts of Syria's Aleppo expressed fears Monday of a lengthy government siege, as food supplies dwindled after regime troops seized the only road into the city's east.

"I don't know what is going to happen to us," said 38-year-old Mohamed Rukby, an unemployed father-of-four in the Bustan al-Qasr neighbourhood.

"We have nowhere to go. All the roads are closed and we've been suffering for days with shortages of bread, food and basically everything," he told AFP.

Food and fuel shortages had already hit the east of the city, home to around 300,000 people, after government forces advanced to within firing range of the key Castello Road supply route on July 7.

(AFP)