Air strikes and clashes in Syria's second city Aleppo killed at least 12 people Wednesday, AFP reports, as part of a surge in violence straining a two-month-old ceasefire.

State news agency SANA said that seven people were killed and 35 wounded by rocket and gunfire in several neighborhoods that it blamed on Al-Qaeda affiliate Al-Nusra Front and its allies.

In rebel-held eastern Aleppo, five civilians were killed in two neighborhoods, according to the civil defense, known as White Helmets.

An AFP correspondent said that regime aircraft targeted one area with barrel bombs and another with missiles.