The United States expressed concern on Tuesday at what it said was the heavy civilian toll of "indiscriminate" Russian air strikes in Syria.

US Secretary of State John Kerry spoke to his Russian counterpart Foreign Minister Sergei Lavrov on Monday and conveyed Washington's worries, AFP reports.

State Department spokesman Mark Toner, citing reports from what he called "credible human rights organizations," said: "Russian air strikes in Syria have killed hundreds of civilians, including first responders, (and) hit medical facilities, schools and markets." Toner added that in October and the first half of November, more than 130,000 Syrians had been forced to flee their homes, in part because of intensified Russian bombing.