Gunmen on motorcycles on Wednesday shot dead seven policemen guarding a polio vaccination team in Pakistan's southern port city Karachi, officials said, a brazen attack in the country's economic hub.

Feroz Shah, a senior police official told AFP that eight gunmen carried out the killings in two separate attacks in the city's western Orangi Town neighborhood.

"The gunmen first opened fire on three policemen in the streets of Orangi Town, killing them all," he said, adding: "Later they shot dead four policemen, who were sitting in a police mobile van" a few streets away.