Israeli aircraft hit the home of Hamas's top leader in Gaza, Ismail Haniyeh, inside the Shati region of Gaza on Monday night, his son said.
"The Israeli enemy struck our house twice," Abed Salam Haniyeh said in a statement quoted by AFP.
The Reuters news agency quoted Gaza’s interior ministry as having said that the airstrike caused damage but no casualties.
An IDF spokeswoman had no information on the report but was checking for details.
Haniyeh served as the prime minister of Hamas’s government in Gaza, but stepped down when Hamas and Palestinian Authority Chairman Mahmoud Abbas’s Fatah movement reached a deal on a unity government.
The Telegraph recently revealed that three of Haniyeh’s sisters are living as full Israeli citizens.
The three, according to the report, married Bedouin and became full citizens 30 years ago. The three now hide in the anonymity of the Israeli desert.
Several of Haniyeh’s relatives have received medical treatment in Israel - including his mother in-law and granddaughter - despite the fact that he has pledged its utter destruction.